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Definition

Peritonitis is an inflammation or infection of the peritoneum. The peritoneum is a thin tissue lining that covers the inside of the abdominal cavity. It also covers the outside of the intestines and other abdominal organs.

There are several types:

  • Primary
  • Secondary
  • Peritoneal dialysis-related

Peritonitis is a serious condition. It requires immediate treatment. If not promptly treated, it can be fatal.

Causes

  • Primary peritonitis—occurs when there is a buildup of fluid in the abdomen. This is called ascites . It is caused by chronic liver disease, among other conditions.
  • Secondary peritonitis—caused by bacteria that enter the abdominal cavity. Can be due to an injury or a condition, such as a ruptured appendix.
  • Dialysis-related peritonitis—caused by bacteria that enter the peritoneal cavity during or after peritoneal dialysis (a treatment for kidney disease).
Secondary Peritonitis
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Risk Factors

A risk factor is something that increases your chance of getting a disease or condition. Risk factors for peritonitis include:

Symptoms

Symptoms may include:

  • Severe pain or tenderness in the abdomen
  • Pain in the abdomen that is worse with motion
  • Bloating of the abdomen
  • Constipation
  • Fever
  • Nausea and vomiting
  • Weakness or dizziness
  • Shortness of breath
  • Rapid pulse or breathing rate
  • Dehydration —signs include dry skin and lips, decreased urine production

Diagnosis

The doctor will ask about your symptoms and medical history, and perform a physical exam. Tests may include:

  • Blood tests
  • Analysis of fluids from the peritoneum
  • Abdominal x-rays —to look for signs of inflammation
  • Laparotomy —surgery to open and examine the abdomen

Treatment

Treatment depends on the cause. It may include:

  • Surgery to repair openings in the skin surface or to remove damaged tissue
  • Antibiotics to treat infection
  • Replacement of fluids

If you are diagnosed with peritonitis, follow your doctor's instructions .

Prevention

There are no guidelines for preventing peritonitis.

Revision Information

  • Reviewer: Daus Mahnke, MD
  • Review Date: 09/2013 -
  • Update Date: 09/30/2013 -
  • American Gastroenterological Association

    http://www.gastro.org

  • The American College of Gastroenterology

    http://www.acg.gi.org

  • Canadian Association of Gastroenterology

    http://www.cag-acg.org

  • Health Canada

    http://www.hc-sc.gc.ca/index-eng.php

  • Feldman M, et al. Sleisenger & Fordtran's Gastrointestinal and Liver Disease. 8th ed. St. Louis: Mosby, 2005.

  • Olendorf D, Jeryan C, Boyden K. Gale Encyclopedia of Medicine . Detroit, MI: Gale Group Research Company; 2000.

  • Peritonitis. Mayo Clinic website. Available at: http://www.mayoclinic.com/health/peritonitis/ds00990 . Updated July 2009. Accessed July 24, 2009.

  • Townsend CM, et al. Sabiston Textbook of Surgery. 17th ed. Philadelphia: Saunders, 2004.

  • Yamada T, Alpers DH, et al. Textbook of Gastroenterology . 4th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2003.